2010 Fiscal Year Final Research Report

Development of the new method for evaluation of vascular function after exercise as a risk assessment for early phase atherosclerosis

Research Project

Project/Area Number	20500622
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Applied health science
Research Institution	Kyoto Prefectural University of Medicine
Principal Investigator	TAKANAMI Yoshikazu Kyoto Prefectural University of Medicine, 家政学部, 教授 (40206777)
Project Period (FY)	2008 – 2010
Keywords	生活習慣病 / 運動負荷 / 血管機能検査 / 動脈硬化 / 血管トーヌス
Research Abstract	The purpose of this study was to establish the method to evaluate an insufficiency of vasodilation after exercise which is considered to be a symptom of an early phase atherosclerosis. Arterial stiffness was used as a marker of vascular function. A transient decrease in arterial stiffness was observed after a medium intensity step exercise. There was an individual difference in this change and this decrease in arterial stiffness was not observed after high fat meal which is considered to impair vascular function. In conclusion, the measurement of arterial stiffness after ten minutes step exercise at medium intensity may be useful to evaluate a symptom of early phase atherosclerosis