2011 Fiscal Year Final Research Report
Theoretical Study on Memory and Cognitive Functions in Hippocampus and Dendritic Information Integration
| Project/Area Number |
20509001
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Sensitivity informatics/Soft computing
|
|---|
| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
OMORI Toshiaki 東京大学, 大学院・新領域創成科学研究科, 助教 (10391898)
|
|---|
| Project Period (FY) |
2008 – 2011
|
| Keywords | 海馬体 / 樹状突起 / 記憶認知機能 / 位相応答曲線 / 膜特性 / 数理モデル / 情報表現 / 情報統合 |
|---|
| Research Abstract |
In this study, we performed theoretical studies using mathematical models in order to investigate relation between dendritic information integration and neuronal information processing such as memory and cognitive functions in hippocampal formation. We showed by analysis and numerical simulations that the impact of sensory inputs given to distal dendrite on somatic response is significantly enhanced by effect of spatial structure of electrical properties over dendrite. Furthermore, we performed theoretical studies using mathematical model for spatial cognition function, one for memory function, and one for information representations of both face angle and face identity. We also clarified an analytical relation between phase response curve and neuronal membrane properties.
|
