2010 Fiscal Year Final Research Report
Multi-dimensional Analysis of Protein Properties and Functional Control of Them by Using Vibration and Optical Methodologies
| Project/Area Number |
20510100
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
KAWASAKI Takayoshi Tokyo Institute of Technology, 大学院・生命理子学研究科, 助教 (60334504)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 水晶発振子 / 金異常反射 / 反射干渉分光法 / 酵素反応 / 振動効果 / リポソーム / DNA / 粘弾性 |
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| Research Abstract |
In this study, we have developed dual mass sensing devices using a quartz crystal microbalance and optical film thickness measuring methods. As the optical system, we utilized newly developed an enhanced anomalous reflection of Au and a reflectometric interference spectroscopy using TiO2/Ti surface. Furthermore, with these simultaneous measuring systems, we could evaluate the physicochemical properties of protein, liposome, and DNA that adsorbed on the surface.
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