2010 Fiscal Year Final Research Report
Spacio-temporal analysis of histone modification by FRET probes
| Project/Area Number |
20510183
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
基礎ゲノム科学
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
TANAKA Yuujirou Tokyo Medical and Dental University, 大学院・疾患生命科学研究部, 准教授 (00311613)
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| Project Period (FY) |
2008 – 2010
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| Keywords | クロマチン構造 / ヒストン修飾 / メチル基転移酵素 / 脱メチル化酵素 |
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| Research Abstract |
A new technique of visualization of histone modifying enzymes was established using FRET peptides and artificially engineered lysyl endopeptidases. The method was successfully employed to visualize intra-cellular histone modifying enzyme activity.
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[Presentation]2010
Organizer
定量生物学の会第3回年会
Place of Presentation
東京大学生産技術研究所
Year and Date
2010-11-26
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