2010 Fiscal Year Final Research Report
Simultaneous EEG/fMRI measurement and event-related analysis for observation of the activation process of P300
| Project/Area Number |
20530667
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Experimental psychology
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| Research Institution | Tokyo Denki University |
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Principal Investigator |
WANG Liqun Tokyo Denki University, 先端工学研究所, 講師 (40312037)
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| Co-Investigator(Kenkyū-buntansha) |
NEMOTO Iku 東京電機大学, 情報環境学部, 教授 (40105672)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 生理 / P300 / EEG / fMRI同時測定 / ヒト高次脳機能 |
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| Research Abstract |
In this study, techniques to measure EEG and fMRI simultaneously were investigated, from which P300 responses evoked by visual stimuli were examined. A unique time scheme of stimulus presentation and fMRI sampling for the oddball paradigm was also designed. Comparing the grand average response of EEG evoked by target events with that evoked by standard events, a significant difference was found in latency range from 280 to 450 ms (P3b component, P<0.001). In the group study of BOLD responses, significant activations appeared, and a temporal progression of the activations from the occipital visual cortex, via the temporoparietal and temporal regions to the prefrontal cortex was estimated based on the results of EEG topography during the period of P3b response.
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