2010 Fiscal Year Final Research Report
Mechanisms of functional differentiation in the Drosophila midgut
| Project/Area Number |
20570004
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Genetics/Genome dynamics
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| Research Institution | Okayama University |
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Principal Investigator |
NAKAGOSHI Hideki Okayama University, 大学院・自然科学研究科, 准教授 (50314662)
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| Project Period (FY) |
2008 – 2010
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| Keywords | ショウジョウバエ / 腸管 / 機能分化 / 金属イオン / 酸 |
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| Research Abstract |
The Drosophila middle midgut has two functions, copper absorption and acid secretion. These functions are established by intercellular communication between copper and interstitial cells. The transcription factor Dve has two isoforms (Dve-A, Dve-B), and the spatio-temporal regulation of isoform switching is cricial for functional differentiation of the midgut. In addition, the cell-type specific activities of Rho GTPase and V-ATPase are also required for the midgut functions.
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Research Products
(7 results)
