2010 Fiscal Year Final Research Report
Genome-wide screening of localized RNAs in Schizosaccharomyces pombe
| Project/Area Number |
20570005
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Genetics/Genome dynamics
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| Research Institution | Kumamoto University (2008, 2010)
Otsuma Women's University Junior College Division (2009) |
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Principal Investigator |
TAKEUCHI Tomoko (安東 知子) Kumamoto University, 短期大学部・家政科, 准教授 (20294548)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 分裂酵母 / RNA / 局在化 |
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| Research Abstract |
In screening of new 5,316 RNAs (6,520 in total), we found 39 candidate RNAs showing subcellular localization. 25 RNAs showed localization as dots in the nucleus, and 5 RNAs and 9 RNAs were localized in the DNA region and in the nucleolus region of the nucleus, respectively. Analysis of 2 RNAs localized in the DNA region revealed that RNA sequences required for the localization were different between the two RNAs. We obtained data suggesting that the RNA sequences of the two RNAs have ability to regulate gene expression.
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