2010 Fiscal Year Final Research Report
Analysis of the novel quorum-sensing mechanism observed in thermo-tolerant evolution process
| Project/Area Number |
20570225
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Evolutionary biology
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| Research Institution | Toho University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
WATANABE Soichiro 東邦大学, 理学部, 准教授 (10287550)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 大腸菌 / 耐熱進化 / クオラムセンシング / 相互作用 |
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| Research Abstract |
Intercellular interaction observed in thermo-tolerant evolution process of E. coli was quorum sensing like growth regulation. This interaction was mainly driven by lactic acid as quorumon. This interaction appeared strongly in early phase in 45 degree adaptation and decreased evolution time-dependently.
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[Journal Article] Transition from positive to neutral in mutation fixation along with continuing rising fitness in thermal adaptive evolution2010
Author(s)
T. Kishimoto, L. Iijima, M. Tatsumi, N. Ono, A. Oyake, T. Hashimoto, M. Matsuo, M. Okubo, S. Suzuki, K. Mori, A. Kashiwagi, C. Furusawa, Bei-Wen Ying, T. Yomo
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Journal Title
PLoS Genetics 6
Pages: e1001164
Peer Reviewed
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[Journal Article] Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S Proteasome.2008
Author(s)
H. Yashiroda, T. Mizushima, K. Okamoto, T. Kameyama, H. Hayashi, T. Kishimoto, S. Niwa, M. Kasahara, E. Kurimoto, E. Sakata, K. Takagi, A. Suzuki, Y. Hirano, S. Murata, K. Kato, T. Yamane, K. Tanaka
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Journal Title
Nature structural & molecular biology 15
Pages: 228-236
Peer Reviewed
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