Characteristics of small GTP binding protein in insect brain

2010 Fiscal Year Final Research Report

• Project/Area Number: 20580053
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Applied entomology
• Research Institution: Kobe University
• Principal Investigator: UNO Tomohide Kobe University, 農学研究科, 准教授 (80240852)
• Project Period (FY): 2008 – 2010
• Keywords: 養蚕 / 蚕糸

Research Abstract

Insect synthesizes neuropeptides and clock-related proteins in the specific cell of small brain. These proteins are synthesized upon stimulation of light and temperature. Finally these proteins cause diapause, eclosion and metamorphosis. To elucidate mechanism of synthesis and secretion of these proteins in the brain, we clarified functional roles of Rab proteins ; the small GTPase family to play essential roles in various aspects of membrane traffic ; in the brain of Bombyx mori.

Research Products

• [Journal Article] Small GTPases of the Rab family in the brain of Bombyx mori Histochemistry and Cell Biology (2010)
  • Author(s): Uno, T., Hata, K., Hiragaki, S., Isoyama, Y., Trang, L.T.D., Uno, Y., Kanamaru, K., Yamagata, H., Nakamura, M., Takagi, M., Takeda, M.
  • Journal Title: 134 Pages: 615-622
  • Peer Reviewed
• [Journal Article] Rab14 from Bombyx mori (Lepidoptera : Bombycidae) shows ATPase activity. (2010)
  • Author(s): Uno, T., Moriwaki, T., Isoyama, Y., Uno, Y., Kanamaru, K., Yamagata, H., Nakamura, M., Takagi, M.
  • Journal Title: Biology Letters 6 Pages: 379-381
  • Peer Reviewed
• [Journal Article] Ferulic acid production in the brewing of rice wine (sake). (2009)
  • Author(s): Uno, T., Itoh, O., Miyamoto, T., Kubo, M., Kanamaru, K., Yamagata, H., Yasufuku,Y., Imaishi, H.
  • Journal Title: Journal of the Institute of Brewing. 115 Pages: 116-121
  • Peer Reviewed
• [Journal Article] Phosphorylation of small GTPases, Rab proteins from Bombyx mori (Lepidoptera : Bombycidae). (2009)
  • Author(s): Uno, T., Hata, K., Trang, L.T.D., Hiragaki, S., Nakada, T., Nakamura, M., Yamagata, H., Kanamaru, K., Takeda, M., Matsubara, M.
  • Journal Title: European Journal of Entomology. 106 Pages: 499-506
  • Peer Reviewed
• [Journal Article] Biochemical characterization of Rab proteins from Bombyx mori (2009)
  • Author(s): Uno, T., Moriwaki, T., Nakamura, M., Matsubara, M., Yamagata, H., Kanamaru, K., Takagi, M.
  • Journal Title: Archives of Insect Biochemistry and Physiology 70 Pages: 77-89
  • Peer Reviewed
• [Presentation] カイコ脳を用いたGTP結合タンパク質(Rab)の免疫組織化学的解析 (2010)
  • Author(s): 磯山侑里・畑圭祐・Le Thi Trang・平垣進・山形裕士・金丸研吾・竹田真木夫・宇野知秀
  • Organizer: 日本蚕糸学会第80回大会
  • Place of Presentation: 信州大学
  • Year and Date: 2010-04-04
• [Presentation] カイコ脳に存在する低分子量GTP結合タンパク質(rab)の機能解析 (2009)
  • Author(s): 畑圭祐、Le Thi Dieu Trang、森脇翼、山形裕士、金丸研吾、竹田真木夫、宇野知秀
  • Organizer: 第79回大会
  • Place of Presentation: 東京農工大学
  • Year and Date: 2009-03-22
• [Presentation] Rab GTPase, small GTP binding proteins, from the brain of Bombyx mori. (2008)
  • Author(s): Hata K., Trang, L.T.D., Moriwaki T., Nakada, T., Hiragaki S., Takagi, M., Kanamaru K., Yamagata H., Takeda M., Uno T.
  • Organizer: Asia-pacific congress of Sericulture and Insect Biotechnology 2008 (APSERI 2008)
  • Place of Presentation: 名古屋大学
  • Year and Date: 20080300
• [Remarks] 科学研究費の社会普及事業[ひらめきときめきサイエンス]
• [Remarks] 昆虫の蛋白質を見てみよう-昆虫を用いた生化学実験 平成23年9月24日実施予定
• [Remarks] 昆虫を見てみよう-カイコの解剖と生化学実験;平成22年9月25日実施
• [Remarks] 昆虫の脳の解明-小さな脳にある不思議な力-平成21年7月25日実施