2010 Fiscal Year Final Research Report
Cell biological study on dermal pathogenesis of parapoxvirus infection
| Project/Area Number |
20580339
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied veterinary science
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| Research Institution | Gifu University |
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Principal Investigator |
INOSHIMA Yasuo Gifu University, 応用生物科学部, 准教授 (20355184)
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| Project Period (FY) |
2008 – 2010
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| Keywords | パラポックスウイルス / 血管内皮増殖因子 / ウシ / ヒツジ / ヤギ / ニホンカモシカ / 感染症 / 血管内皮細胞 |
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| Research Abstract |
Although parapoxvirus (PPV) infections appear in cattle, sheep and goats, the papular, nodular, pustular and ulcerated skin lesions of Japanese serows (Capricornis crispus) are significantly more severe than those of other animals. Our results from cell biological investigations suggest that high responsiveness to viral endothelial growth factor of endothelial cells might be involved in the severe proliferative skin lesions induced by PPV infection in Japanese serows.
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