2012 Fiscal Year Final Research Report
Searching genes susceptible for life-style related diseases, such as diabetes and hypertension.
Project/Area Number |
20590595
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Hygiene
|
Research Institution | Yamagata University |
Principal Investigator |
DAIMON Makoto 山形大学, 大学院・医学研究科, 准教授 (20241698)
|
Project Period (FY) |
2008 – 2012
|
Keywords | 分子遺伝疫学 |
Research Abstract |
Most studies to find genes susceptible for life-style related diseases have been conducted without regard for life-style per se. This strategy conveys a risk that the results obtained were not useful in ordinary clinical settings. Therefore, we search genes susceptible for life-style related diseases with detailed information of life-styles such as nutritional intakes and physical activities, and found several genes susceptible for life-style related diseases. Of them, tow genes (GNB3 and FTO) were found as associated with diabetes in relation with salt intake and obesity in relation with physical activities, respectively. These findings seem to be very useful in ordinary clinical settings.
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