The living body impact statement of the nanoparticle by the magnetic mesurement

2010 Fiscal Year Final Research Report

• Project/Area Number: 20590612
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Hygiene
• Research Institution: Kitasato University
• Principal Investigator: KUDO Yuichiro Kitasato University, 医学部, 講師 (60348505)
• Co-Investigator(Kenkyū-buntansha): AIZAWA Yoshiharu 北里大学, 医学部, 教授 (10124926) ; TSUNODA Masashi 北里大学, 医学部, 准教授 (00271221) ; SATO Toshihiko 北里大学, 医学部, 准教授 (10225972) ; MIKI Takeo 北里大学, 医学部, 非常勤講師 (00327397) ; KOTANI Makoto 北里大学, 医学部, 客員教授 (60057205)
• Project Period (FY): 2008 – 2010
• Keywords: 肺磁界測定法 / 緩和 / クリアランス / 肺障害性 / フラーレン / ナノ粒子

Research Abstract

I used lungs magnetic field mensuration, and the living body of PCBM which was the fullerene which was the one of the nanoparticles and the derivative evaluated influencing it in this study. A 0.5ml trachea administered fullerene and PCBM to six male Wister rats. For outside magnetization, I measured the residual magnetic field that occurred from a rat afterwards for 20 minutes. In addition, I plotted a residual magnetic field just after the magnetization of each measurement day and demanded the clearance from four three oxidation iron lungs. As for the residual magnetic field and the clearance, fullerene and a PCBM treated group were normal together. The lungs disorder characteristics of PCBM were not thought to be fullerene in the observation periods from the above to three dosage back issues.