2010 Fiscal Year Final Research Report

Evaluation of the postmenopausal ovarian function in hospital based case-control study

Research Project

Project/Area Number	20590646
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Public health/Health science
Research Institution	The University of Tokushima
Principal Investigator	UEMURA Hirokazu The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 准教授 (50346590)
Co-Investigator(Kenkyū-buntansha)	ARISAWA Kokichi 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (30203384) HIYOSHI Mineyoshi 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 学術研究員(特任助教) (30363162)
Project Period (FY)	2008 – 2010
Keywords	自然閉経 / 両側卵巣摘出 / 動脈硬化 / 脈派伝播速度 / 中心性肥満 / 骨密度
Research Abstract	As age or obesity indexes increased, and as ovarian function decreased, the values of the brachial-to-ankle pulse wave velocity (baPWV) increased, that is to say, the vascular elasticity decreased. Age-adjusted means of bone mineral density of the lumbar spines and baPWV as well as circulating estradiol, LH and FSH levels did not differ between women with natural menopause and those with surgical menopause (bilateral oophorectomy). When a value of baPWV was assessed, abdominal circumference of 80 cm might be proper as criteria of the central obesity in Japanese women, and it was thought to be desirable to establish detailed criteria of the central obesity according to their body height.