2010 Fiscal Year Final Research Report
Postmortem genetic analysis for calcium-dependent signal transduction molecules in sudden unexplained death cases
| Project/Area Number |
20590691
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Legal medicine
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| Research Institution | Osaka Medical College |
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Principal Investigator |
SUZUKI Kouichi Osaka Medical College, 医学部, 教授 (60171211)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 法医病理学 |
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| Research Abstract |
This study intended to examine whether fatal arrhythmogenic diseases are involved in sudden unexplained death. Postmortem genetic analysis revealed that three cases of psychiatric patients possessed the ryanodine receptor gene mutations. From the forensic point of view, postmortem genetic analysis for fatal arrhythmogenic diseases is important to obtain information on cause of death. It may also be useful for preventing living family member carriers from preventing possible cardiac events.
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