2010 Fiscal Year Final Research Report
Clarification of new mechanism of ischemic heart disease through periodontitis and identification of cause periodontitis bacterium
Project/Area Number |
20590829
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Circulatory organs internal medicine
|
Research Institution | Kumamoto University |
Principal Investigator |
SOEJIMA Hirofumi Kumamoto University, 保健センター, 准教授 (80332881)
|
Project Period (FY) |
2008 – 2010
|
Keywords | 歯周病スコア / 歯周病菌 / 冠動脈 / プラーク / mRNA / 冠動脈形成術 / 高感度c-reactive protein / 急性冠症候群 |
Research Abstract |
The relativity of the periodontitis severity and high sensitivity c-reactive protein that was the index of the inflammatory reaction of the whole body was proven. A part of coronary plaque contents adheres to the balloon after the coronary intervention. The detection of the periodontitis bacterium was tried from this balloon adhesion thing by polymerase chain reaction, then, mRNA of Prevotella intermedia and Porphyromonas gingivalis was detected.
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Research Products
(18 results)