2010 Fiscal Year Final Research Report
Is anterior cerebral hypoperfusion after response to acute ECT a predictor of relapse tendency in depression?
| Project/Area Number |
20591388
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Tohoku University |
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Principal Investigator |
SUZUKI Kazumasa Tohoku University, 大学院・医学系研究科, 非常勤講師 (20312572)
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| Co-Investigator(Renkei-kenkyūsha) |
KINOMURA Shigeo 東北大学, 大学院・医学系研究科, 非常勤講師 (70281996)
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| Project Period (FY) |
2008 – 2010
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| Keywords | ECT / SPECT / うつ病 |
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| Research Abstract |
We studied relationship relapse-tendency after response to acute ECT and cerebral perfusion detected by SPECT in depression. We followed 22 depressive patients who responded to acute ECT for 6 months. Six patients relapsed and the other 16 patients kept remission. We analyzed cerebral perfusion(SPECT)with SnPM. We found that relapsed patients group indicated sufficiently anterior cerebral hypoperhusion after response to acute ECT compared to non-relapsed patients group. We speculate that the persistent anterior hypoperfusion may underlie relapse tendency in depression.
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[Journal Article] Catatonia in Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition.2010
Author(s)
Francis A, Fink M, Appiani F, Bertelsen A, Bolwig TG, Braunig P, Caroff SN, Carroll BT, Cavanna AE, Cohen D, Cottencin O, Cuesta MJ, Daniels J, Dhossche D, Fricchione GL, Gazdag G, Ghaziuddin N, Healy D, Klein D, Kruger S, Lee JW, Mann SC, Mazurek M, McCall WV, McDaniel WW, Northoff G, Peralta V, Petrides G, Rosebush P, Rummans TA, Shorter E, Suzuki K, Thomas P, Vaiva G, Wachtel L.
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Journal Title
J ECT. 26(4)
Pages: 246-7
Peer Reviewed
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