2010 Fiscal Year Final Research Report
Developmental change of prefrontal function in children with Autism spectrum disorders
| Project/Area Number |
20591391
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
WATANABE Keiichiro The University of Tokyo, 学生相談ネットワーク本部, 講師 (10323586)
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| Co-Investigator(Kenkyū-buntansha) |
KAWAKUBO Yuki 東京大学, 医学部付属病院, 特任助教 (40396718)
KIM Sooyung 東京大学, 医学部附属病院, 特任助教 (90401108)
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| Co-Investigator(Renkei-kenkyūsha) |
ISHII Ayaka 東京大学, 医学部付属病院, 助教 (40609020)
KASAI Kiyoto 東京大学, 医学部附属病院, 教授 (80322056)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 発達障害 / 神経心理 / 脳・神経 / 自閉症 / 認知科学 |
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| Research Abstract |
The aim of this study was exploring the developmental change of prefrontal function in children with autism spectrum disorders (ASD) using the near-infrared spectroscopy. In the typically developing children, the relative change of oxy-hemoglobin was correlated with their age. On the other hand, children with ASD presented the smaller change than age- and IQ-matched typically developing children. Furthermore, there were no correlations between the oxy-hemoglobin and their age.
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[Journal Article] Task dependent prefrontal dysfunction in persons with Asperger's disorder investigated with multi-channel near-infrared spectroscopy.2011
Author(s)
Iwanami A., Okajima Y, Ota H, Tani M, Yamada T, Hashimoto R, Kanai C, Watanabe H, Yamasue H, Kawakubo Y, Kato N
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Journal Title
Research in Autism Spectrum Disorders 5(3)
Pages: 1187-1193
Peer Reviewed
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[Journal Article] Association study of the commonly recognized breakpoints in chromosome 15q11-q13 in Japanese autistic patients2008
Author(s)
C.Kato, M.Tochigi, S.Koishi, Y.Kawakubo, K.Yamamoto, H.Matsumoto, O.Hashimoto, S.Y.Kim, K.Watanabe, Y., 他
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Journal Title
Pgychiatr Genet 18
Pages: 133-136
Peer Reviewed
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[Journal Article] Associations study of the 15q11-q13 maternal expression domain in Japanese autistic patients2008
Author(s)
C.Kato, M.Tochigi, J.Ohashi, S.Koishi, Y.Kawakubo, K.Yamamoto, H.Matsumoto, O.Hashimoto, S.Y.Kim, K.Watanabe, 他
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Journal Title
Am J Med Genet B Neuropsychiatr Genet 147
Pages: 1008-1012
Peer Reviewed
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[Journal Article] No association between the ryanodine receptor 3 gene and autism in a Japanese population2008
Author(s)
M.Tochigi, C.Kato, J.Ohashi, S.Koishi, Y.Kawakubo,, K.Yamamoto, H.Matsumoto, O.Hashimoto, S.Y.Kim, K.Watanabe, Y.Kmmo, E.
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Journal Title
Psychiatry Clin Neurosci 62
Pages: 341-344
Peer Reviewed
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