2010 Fiscal Year Final Research Report
Development of algorithm for quantification of regional myocardial blood flow in patients with ischemic heart disease using 82Rb PET
| Project/Area Number |
20591431
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Hokkaido University |
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Principal Investigator |
KATOH Chietsugu Hokkaido University, 大学院・保健科学研究院, 准教授 (10292012)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHINAGA Keiichirou 北海道大学, 大学院・医学研究科, 准教授 (30435961)
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| Co-Investigator(Renkei-kenkyūsha) |
SHIGA Tohru 北海道大学, 大学院・医学研究科, 講師 (80374495)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 虚血性心疾患 / PET / ルビジウム82 / 心筋血流 / 定量測定 |
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| Research Abstract |
Three-dimensional (3D) PET with 82Rb yields myocardial image data with much spillover fraction from the blood. To calculate the regional myocardial blood flow (MBF) with 82Rb myocardial 3D PET, we developed a new algorithm to suppress the spillover using a non-uniform least squared fitting with a weighted function using a blood time-activity curve.
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