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2010 Fiscal Year Final Research Report

Improvement of the stabilization on the target coronary artery motion by 3-dimensional digital motion capture and reconstruction technology.

Research Project

  • PDF
Project/Area Number 20591651
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionFukushima Medical University

Principal Investigator

YOKOYAMA Hitoshi  Fukushima Medical University, 医学部, 教授 (80282127)

Co-Investigator(Kenkyū-buntansha) TAKASE Shinya  福島県立医科大学, 医学部, 講師 (30347223)
WAKAMATSU Hiroki  福島県立医科大学, 医学部, 講師 (50443875)
Co-Investigator(Renkei-kenkyūsha) OMATA Sadao  日本大学, 工学部, 教授 (90060186)
Project Period (FY) 2008 – 2010
Keywords外科 / 心臓 / 心拍動下手術
Research Abstract

Adequate stabilization of anastomosis sites during off-pump coronary artery bypass is essential to obtain excellent graft patency. We examined the effect of several drugs and mechanical ventilation on the target coronary artery motion by three-dimensional digital motion capture and reconstruction technology.
Selective beta-1 receptor blockade significantly reduces the three dimensional motion at anastomosis sites on the beating heart.
Low volume or postponement of ventilation might be beneficial to excellent coronary artery stabilization during OPCAB surgery.
The heart rate during remifentanil infusion significantly decreased at all stabilized areas. But we revealed that target coronary artery motion under mechanical stabilizers does not increase after remifentanil administration.
Noradrenarine significantly increases target coronary artery motion under a beating heart, whereas Phenylephrine does not. Phenylephrine is apparently more suitable for treating hypotension that develops during OPCAB.

  • Research Products

    (12 results)

All 2010 2009 2008

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (5 results) Book (1 results)

  • [Journal Article] Selective beta-1 receptor blockade further reduces the mechanically stabilized target coronary artery motion during beating heart surgery.2010

    • Author(s)
      Wakamatsu H, Yokoyama H
    • Journal Title

      Innovations 5

      Pages: 349-354

    • Peer Reviewed
  • [Journal Article] Landiolol reduces coronary artery motion in an open chest porcine model : Implication for off-pump coronary artery bypass surgery.2010

    • Author(s)
      Wakamatsu H, Yokoyama H
    • Journal Title

      Gen Thorac Cardiovasc Surg 63

      Pages: 764-768

    • Peer Reviewed
  • [Journal Article] Short-term and long-term outcome of the octogenerians after off-pump coronary artery bypass surgery.2010

    • Author(s)
      Takase S, Wakamatsu H, Yokoyama H
    • Journal Title

      Gen Thorac Cardiovasc Surg 58

      Pages: 561-567

    • Peer Reviewed
  • [Journal Article] Comparison of endovascular laser treatment for varicose veins with high ligation using pulse mode and without high ligation using continuous mode and lower energy.2010

    • Author(s)
      Satokawa H, Yokoyama H, Wakamatsu H, Igarashi T.
    • Journal Title

      Ann Vasc Dis 3

      Pages: 46-51

    • Peer Reviewed
  • [Journal Article] 統合的CABGアルゴリズムによるOPCAB安全性の向上:ラーニングカーブ初期からの戦略と手技2009

    • Author(s)
      横山斉
    • Journal Title

      胸部外科 62

      Pages: 28-33

    • Peer Reviewed
  • [Journal Article] Aortic arch repair with coronary artery revascularization.2009

    • Author(s)
      Wakamatsu H, Sato Y, Takase S, Sato Y, Satokawa H, Yokoyama H
    • Journal Title

      Fukushima J Med Aci 55

      Pages: 52-60

    • Peer Reviewed
  • [Presentation] 「我が国のCABGの現況:標準術式としてのOPCABの成績からガイドラインを再考する」:日本冠疾患学会・冠動脈外科学会ジョイントシンポジウム「冠血行再建のより良いガイドラインにむけて」2010

    • Author(s)
      横山斉
    • Organizer
      第15回日本冠動脈外科学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-07-30
  • [Presentation] Roles of beta1-blocker during off-pump coronary artery bypass2010

    • Author(s)
      横山斉
    • Organizer
      Current Seminar in Osaka 2010
    • Place of Presentation
      大阪
    • Year and Date
      2010-07-10
  • [Presentation] 心臓血管外科の現状と展望2010

    • Author(s)
      横山斉
    • Organizer
      札幌胸部外科フォーラム
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-24
  • [Presentation] OPCAB冠動脈吻合:外科医のベストパフォーマンスのために2010

    • Author(s)
      横山斉
    • Organizer
      関西胸部外科学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-06-24
  • [Presentation] 心拍動下冠動脈バイパス術の長期成績とその優位性-OPCABを中心とした統合的冠動脈再建法421例の検討から-2010

    • Author(s)
      高瀬信弥、佐戸川弘之、若松大樹、横山斉
    • Organizer
      第110回日本外科学会定期学術集会
    • Place of Presentation
      名古屋(シンポジウム)
    • Year and Date
      2010-04-09
  • [Book] 福島の進路 No.316発行(「心臓血管外科における最新治療と産学共同研究」)2008

    • Author(s)
      若松大樹
    • Total Pages
      26-29
    • Publisher
      (財)福島経済研究所(2008.11.26発行)

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Published: 2012-01-26   Modified: 2016-04-21  

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