2010 Fiscal Year Final Research Report
Reducing implant infection using the bactericidal effect of photocatalytic titanium dioxide
| Project/Area Number |
20591761
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Nagasaki University |
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Principal Investigator |
KOSEKI Hironobu Nagasaki University, 医歯薬学総合研究科, 客員研究員 (70457571)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 生体材料 / 細菌 / 感染症 / 酸化チタン |
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| Research Abstract |
Basic research and animal studies were conducted on the bactericidal effect of photocatalytic titanium dioxide (TiO2) against infectious diseases caused by microorganisms (particularly intraoperative infections). Effective bactericidal effects against various staphylococci were observed when a TiO2 film was applied to metal surfaces used during surgery and when an aqueous solution of ultrafine TiO2 particles was used. There was no evidence suggesting toxicity or harmful effects on living cells or tissues. The TiO2 developed in this research has the potential for use as a therapeutic method to help patients suffering from various infectious diseases.
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