2010 Fiscal Year Final Research Report
Expression of microRNAs in prostate cancer
| Project/Area Number |
20591853
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | University of Fukui |
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Principal Investigator |
ITO Hideaki University of Fukui, 医学部, 助教 (00345620)
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| Co-Investigator(Kenkyū-buntansha) |
YOKOYAMA Osamu 福井大学, 医学部, 教授 (90242552)
OYAMA Nobuyuki 福井大学, 医学部付属病院, 講師 (20223977)
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| Co-Investigator(Renkei-kenkyūsha) |
ITO Hiroshi 福井大学, 医学部, 教授 (80253847)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 前立腺癌 / miRNA / Gleason grade |
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| Research Abstract |
Although the expression levels of miR-31, -205, -221, -222 were significantly suppressed in cancer cells comparing with normal prostatic cells in prostate cancer samples, the expression levels were not different between each Gleason grade. The expression levels of miR-183 and -205 in Gleason grade 4 samples increased with increasing Gleason score of the patient.
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