2010 Fiscal Year Final Research Report
Development of novel gene therapy for hormone refractory prostate cancer
| Project/Area Number |
20591868
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Jikei University School of Medicine |
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Principal Investigator |
KIYOTA Hiroshi Jikei University School of Medicine, 医学部, 准教授 (30153240)
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| Co-Investigator(Kenkyū-buntansha) |
KIMURA Takahiro 東京慈恵会医科大学, 医学部, 助教 (00307430)
MIKI Jun 東京慈恵会医科大学, 医学部, 助教 (00328361)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 癌 / 泌尿器科 / 前立腺癌 / 遺伝子治療 |
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| Research Abstract |
The aim of this study is to develop the new gene therapy using lentiviral vector with prostate-specific promoter that induces therapeutic gene to prostate cancer specifically. Lentiviral vectors with prostate-specific promoters were constructed and the efficiency was observed in vitro and in vivo models.
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