2010 Fiscal Year Final Research Report
The clinical analysis to induction of Japanese cedar pollinosis in pollen challenge chamber
| Project/Area Number |
20592006
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Osaka Medical College |
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Principal Investigator |
TAKENAKA Hiroshi Osaka Medical College, 学長 (40137162)
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| Co-Investigator(Kenkyū-buntansha) |
HYO Sawako 大阪医科大学, 非常勤医師 (50469219)
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| Project Period (FY) |
2008 – 2010
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| Keywords | スギ花粉症 / 花粉曝露質 / ヒト非シーズンスギ花粉症発症モデル / 薬効検定 / RCT |
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| Research Abstract |
More than 25% of Japanese seems to be suffered on Japanese cedar pollinosis. However, annual pollen dispersion was depend on weather and latitude of the land. So, there are few evidences about the standard drug therapy of Japanese cedar pollinosis.
Our pollen challenge chamber, have to make constant pollen dispersion to the person in the room, was examined for clinical experiment. The temporal and spatial variations of the pollen level in the chamber were small, facilitating stable pollen challenge, and pollinosis symptoms were induced in the volunteers with cedar pollinosis. The challenge chamber may be useful to judge the effects of therapy against pollinosis.
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