2010 Fiscal Year Final Research Report
Corneal Tissue Engineering Using Alginate
| Project/Area Number |
20592083
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Doshisha University |
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Principal Investigator |
KOIZUMI Noriko Doshisha University, 生命医科学部, 教授 (20373087)
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| Co-Investigator(Kenkyū-buntansha) |
KINOSHITA Shigeru 京都府立医科大学, 医学研究科, 教授 (30116024)
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| Research Collaborator |
TORII Ryuzou 滋賀医科大学, 動物生命科学研究センター, 教授 (50106647)
OKUMURA Naoki 京都府立医科大学, 眼科, 病院助教 (10581499)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 角膜再生医療 / アルジネート / 細胞移植 |
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| Research Abstract |
We tried to develop a new cryopreservation method for human corneal tissue using alginate encapsulation and we studied the feasibility of cultivated corneal endothelial cell transplantation using a corneal lamellar graft. We cultivated monkey corneal endothelial cells on a frozen preserved human corneal lamellar graft and successfully transplanted this construct into animal eyes. Our results suggest the possibility of cultivated corneal endothelial cell transplantation using a frozen preserved corneal lamellar graft.
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Research Products
(13 results)
