2010 Fiscal Year Final Research Report
The relationship between the periodicity of incremental lines in the tooth dentin and a biological clock : Regulation by melatonin
| Project/Area Number |
20592168
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Kochi Gakuen College |
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Principal Investigator |
MISHIMA Hiroyuki Kochi Gakuen College, 教授 (30112957)
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| Co-Investigator(Kenkyū-buntansha) |
TABATA J Makoto 東京医科歯科大学, 院医歯学総合研究科, 准教授 (20243248)
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| Co-Investigator(Renkei-kenkyūsha) |
SUZUKI Nobuo 金沢大学, 環日本海域環境研究センター, 准教授 (60242476)
HATTORI Atsuhiko 東京医科歯科大学, 教養部, 教授 (70183910)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 遺伝子 / 細胞・組織 / 歯学 / 成長線 / メラトニン |
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| Research Abstract |
It became clear that the melatonin receptors MT1 and MT2 were present in the tooth embryo. The level of melatonin concentration during the night time was higher than that of the daytime. The dark-staining layer of hematoxylin was observed at the calcification front of dentin formed during the night time. It is considered that calcification advances during night periods, when the dark-staining layer of hematoxylin is formed, while the light-staining layer is formed during the daytime. It is suggested that melatonin may participate in the periodicity of the incremental lines of dentin.
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[Journal Article] Monohydroxylated polycyclic aromatic hydrocarbons inhibit booth osteoclastic and asteoblastic activies in teleost scale2009
Author(s)
Suzuki N., Hayakawa K., Kameda K., Triba A., Tang., Tabata M. J., Takada K., Wada S., Omori K., Srivastav A.K., Mishima H., Hatttori A
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Journal Title
Life Sciences 84
Pages: 482-488
Peer Reviewed
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