Three-dimensional analysis of dental titanium implant coated by a new biomaterial

2010 Fiscal Year Final Research Report

• Project/Area Number: 20592200
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Pathobiological dentistry/Dental radiology
• Research Institution: Okayama University
• Principal Investigator: TAKAGI Shin Okayama University, 大学院・医歯薬学総合研究科, 准教授 (40116471)
• Co-Investigator(Kenkyū-buntansha): NAGAI Noriyuki 岡山大学, 名誉教授 (90085770) ; NAGATSUKA Hitoshi 岡山大学, 大学院・医歯薬学総合研究科, 教授 (70237535) ; MIZUKAWA Nobuyoshi 岡山大学, 岡山大学病院, 講師 (00263608) ; TAMAMURA Ryou 岡山大学, 大学院・医歯薬学総合研究科, 助教 (00403494) ; KISHIMOTO Etsuo 岡山大学, 大学院・医歯薬学総合研究科, 准教授 (20091316)
• Project Period (FY): 2008 – 2010
• Keywords: チタン酸カルシウム / コーティング材 / インプラント / 歯科材料 / 骨結合

Research Abstract

In this study, we analyzed the effect of CaTiO3-C coating material in vitro and in vivo. Cells cultured on CaTiO3-C coated Ti plates showed good cellular proliferation and osteoblastic differentiation. Furthermore, CaTiO3-C coated implant showed satisfying bone attachment. These results suggest that CaTiO3-C plays a dominant effect on tissue response, and could be considered as a useful biomaterial for dental implants.

Research Products

• [Journal Article] Effect of CaTiO(3)-CaCO(3) prepared by alkoxide method on cell response. (2010)
  • Author(s): Rodriguez AP, Inoue M, Tanaka T, Miyake M, Sfer AM, Kishimoto E, Tsujigiwa H, Rivera RS, Nagatsuka H.
  • Journal Title: J Biomed Mater Res A. 93(1) Pages: 297-303
  • Peer Reviewed
• [Journal Article] Effect of a new titanium coating material (CaTiO3-aC) prepared by thermal decomposition method on osteoblastic cell response. (2010)
  • Author(s): Inoue M, Rodriguez AP, Takagi T, Katase N, Kubota M, Nagai N, Nagatsuka H, Inoue M, Nagaoka N, Takagi S, Suzuki K.
  • Journal Title: J Biomater Appl. 24(7) Pages: 657-672
  • Peer Reviewed
• [Journal Article] Chemical Analysis of a Novel Coating Material, CaTiO3-aC. (2008)
  • Author(s): Okauchi-Yabuuchi M, Tamamura R, Nagaoka N, Takagi S, Kishimoto E, Takagi T, Rodriguez A, Inoue M, Nagatsuka H, Akao M, Nagai N.
  • Journal Title: Journal of Hard Tissue Biology. 17(3) Pages: 115-120
  • Peer Reviewed
• [Presentation] 新規コーティング材CaTiO3-aCの細胞生物学的・組織学的検討 (2010)
  • Author(s): 平田泰久
  • Organizer: 第19回硬組織再生生物学会総会・学術大会
  • Place of Presentation: 岡山
  • Year and Date: 2010-09-04
• [Presentation] 新規コーティング材CaTiO3-aCの組織学的検討 (2009)
  • Author(s): 玉村亮
  • Organizer: 第18回硬組織再生生物学会総会・学術大会
  • Place of Presentation: 札幌
  • Year and Date: 2009-09-05
• [Presentation] 新規生体材料(チタン酸カルシウム-非晶質炭素複合物CaTiO3-aC)の細胞学的検討 (2008)
  • Author(s): 松田寛之
  • Organizer: 第17回硬組織再生生物学会総会・学術大会
  • Place of Presentation: 徳島
  • Year and Date: 2008-08-30