2010 Fiscal Year Final Research Report
Oral soft tissue reconstruction using bioresorbable polymer stent
| Project/Area Number |
20592297
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
TACHIKAWA Noriko Tokyo Medical and Dental University, 歯学部附属病院, 講師 (70236537)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 生分解性ポリマー / ポリ乳酸 / 軟組織再建 / 歯科インプラント |
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| Research Abstract |
Little has been developed in the field of biomaterials for soft tissue reconstruction, and most of the materials available are used in the regeneration of hard tissues. In this study, bioresorbable porous poly-dl-lactide (PdlLA) blocks were implanted on rat calvaria, and were assessed by histologic examination. NIH 3T3 mouse embryo fibroblast cells were cultured on the PdlLA blocks to evaluate initial cell adhesion, cell proliferation. It might be suggested that bioresorbable porous PdlLA block is extremely effective materials used for soft tissue regeneration.
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