Oral soft tissue reconstruction using bioresorbable polymer stent

Research Project

Project/Area Number	20592297
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Dental engineering/Regenerative dentistry
Research Institution	Tokyo Medical and Dental University
Principal Investigator	TACHIKAWA Noriko Tokyo Medical and Dental University, 歯学部附属病院, 講師 (70236537)
Project Period (FY)	2008 – 2010
Project Status	Completed (Fiscal Year 2010)
Budget Amount *help	¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000) Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000) Fiscal Year 2008: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords	生分解性ポリマー / ポリ乳酸 / 軟組織再建 / 歯科インプラント
Research Abstract	Little has been developed in the field of biomaterials for soft tissue reconstruction, and most of the materials available are used in the regeneration of hard tissues. In this study, bioresorbable porous poly-dl-lactide (PdlLA) blocks were implanted on rat calvaria, and were assessed by histologic examination. NIH 3T3 mouse embryo fibroblast cells were cultured on the PdlLA blocks to evaluate initial cell adhesion, cell proliferation. It might be suggested that bioresorbable porous PdlLA block is extremely effective materials used for soft tissue regeneration.

Report

(4 results)