2010 Fiscal Year Final Research Report
A novel diagnostic method of oral inflammation using salivary myeloperoxidase
| Project/Area Number |
20592445
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
KANEHIRA Takashi Hokkaido University, 病院, 講師 (90194935)
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| Co-Investigator(Kenkyū-buntansha) |
TAKEHARA Junji 北海道大学, 大学院・歯学研究科, 助教 (60216934)
MORITA Manabu 岡山大学, 医歯薬学総合研究科, 教授 (40157904)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 唾液 / 口腔炎症 / ミエロペルオキシダーゼ / スクリーニング |
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| Research Abstract |
We investigated the relationship between salivary myeloperoxidase (MPO) levels and morbidity in periodontal disease. The results revealed that measuring salivary MPO levels was useful for screening for periodontal disease. Our findings further suggested that quantitative analysis of salivary MPO is of value for assessing the efficacy of initial preparation for treatment of periodontal disease and for detecting inflammatory conditions of the oral cavity, including pericoronitis of the wisdom teeth.
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