2010 Fiscal Year Final Research Report
Analysis of autophagy in cancer and new strategies for cancer therapy.
| Project/Area Number |
20599013
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
General surgery
|
|---|
| Research Institution | Kumamoto University |
|---|
Principal Investigator |
HASHIMOTO Daisuke Kumamoto University, 医学部附属病院, 非常勤診療医師 (80508507)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
BABA Hideo 熊本大学, 大学院・生命科学研究部, 教授 (20240905)
OHMURAYA Masaki 熊本大学, 大学院・先導機構, 特任助教 (60398229)
TANAKA Hiroshi 熊本大学, 医学部附属病院, 非常勤診療医師 (70452901)
SAKAMOTO Yasuo 熊本大学, 医学部附属病院, 医員 (00452897)
OZAKI Nobuyuki 熊本大学, 医学部附属病院, 非常勤診療医師 (40551255)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Keywords | オートファジー / 消化器癌の発生 / 消化器癌の発育 / 補助療法 |
|---|
| Research Abstract |
Autophagy was induced in pancreatic cancer cell line by anticancer agents and irradiation. Suppression of autophagy resulted in the augmentation of anticancer drug-induced cell death. This result suggested that autophagy might have the cytoprotective effect on anticancer drug-induced cell death in pancreatic cancer cell.
|
-
-
[Journal Article] Trichoblastic carcinoma arising from colostomy.2011
Author(s)
Hashimoto D, Kuroki H, Motomura Y, Ishikawa S, Inayoshi A, Udaka N, Tanoue T, Arita T, Hiroto M, Yagi Y, Baba H.
-
Journal Title
Peer Reviewed
-
[Journal Article] Umbilicus Saving Three-Port Laparoscopic Cholecystectomy.2011
Author(s)
Hashimoto D, Hirota M, Sakata K, Hirata K, Kiyota Y, Ishikawa S, Tanoue T, Inayoshi A, Arita T, Yagi Y, Baba, H.
-
Journal Title
WebmedCentral LAPAROSCOPY 2(4)
Pages: WMC001882
Peer Reviewed
-
-
[Journal Article] Detection of liver metastases secondary to pancreatic cancer : utility of combined helical computed tomography during arterial portography with biphasic computed tomography-assisted hepatic arteriography.2010
Author(s)
Ikuta Y, Takamori H, Ikeda O, Tanaka T, Sakamoto Y, Hashimoto D, Ozaki N, Nakahara O, Furuhashi S, Abe S, Beppu T, Shimada S, Yamashita Y, Baba H.
-
Journal Title
J Gastroenterol 45(12)
Pages: 1241-1246
Peer Reviewed
-
[Journal Article] Is Estimation of physiologic ability and surgical stress (E-PASS) able to predict operative morbidity after pancreaticoduodenectomy?2010
Author(s)
Hashimoto D, Takamori H, Sakamoto Y, Ikuta Y, Nakahara O, Furuhashi S, Tanaka H, Watanabe M, Beppu T, Hirota M, Baba H.
-
Journal Title
J Hepatobiliary Pancreat Sci. 17(2)
Pages: 132-138
Peer Reviewed
-
-
[Journal Article] Acute afferent loop necrosis after Roux-en-Y cholangiojejunostomy2010
Author(s)
Hashimoto D, Arita T, Kuroki H, Motomura Y, Ishikawa S, Inayoshi A, Udaka N, Tanoue T, Hiroto M, Yagi Y, Baba H.
-
Journal Title
Clin J Gastroenterol. 3(3)
Pages: 165-167
Peer Reviewed
-
[Journal Article] Significance of Endothelial Molecular Markers in the Severity Evaluation of Acute Pancreatitis.2009
Author(s)
Ida S, Fujiyama Y, Hirota M, Imamura Y, Ozaki N, Suyama K, Hashimoto D, Ohmuraya M, Tanaka H, Takamori H, Baba H.
-
Journal Title
Surg Today. 39(4)
Pages: 314-319
Peer Reviewed
-
-
-
-
-
-
[Journal Article] Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells.2008
Author(s)
Hashimoto D, Ohmuraya M, Hirota M, Yamamoto A, Suyama K, Ida S, Okumura Y, Takahashi E, Kido H, Araki K, Baba H, Mizushima N, Yamamura K.
-
Journal Title
J Cell Biol. 30;181(7)
Pages: 1065-1072
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Book] Laparoscopy(Laparoscopy-assisted distal pancreatectomy.)2011
Author(s)
Hirota M, Hashimoto D, Sakata K, Kuroki H, Tanaka Y, Ishiko T, Motomura Y, Ishikawa S, Kiyota Y, Arita T, Inayoshi A, Yagi Y.
Total Pages
ISBN : 978-953-307-205-0.
Publisher
published by InTech(Australia).(in press)
-
-
