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2009 Fiscal Year Final Research Report

Synthesis of Structurally Well-defined Polymers via Microflow System Controlled Polymerization

Research Project

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Project/Area Number 20750077
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Synthetic chemistry
Research InstitutionKyoto University

Principal Investigator

NAGAKI Aiichiro  Kyoto University, 大学院・工学研究科, 助教 (80452275)

Project Period (FY) 2008 – 2009
Keywordsマイクロ化学 / 有機合成化学 / 高分子化学
Research Abstract

We have developed the synthesis of structurally well-defined polymers via microflow system controlled polymerization. In this research, we have found that the use of microflow system could be effective method for (1) controlled cationic polymerization of vinyl monomer (2) controlled anionic polymerization of vinyl monomer (3) the development of the reaction based on the livingness of the polymer chain end (4)integrated and combinatorial synthesis of structurally defined block copolymers.

  • Research Products

    (28 results)

All 2010 2009 2008

All Journal Article (15 results) Presentation (8 results) Book (5 results)

  • [Journal Article] Generations and Reactions of Cyano-Substituted Aryllithium Compounds Using Microreactors2010

    • Author(s)
      Nagaki, A.; Kim, H.; Matuo, C.; Yoshida, J.
    • Journal Title

      Org. Biomol. Chem. 8

      Pages: 1212-1217

  • [Journal Article] Nitro-Substituted Aryl Lithium Compounds in Microreactor Synthesis: Switch between Kinetic and Thermodynamic Contro2009

    • Author(s)
      Nagaki, A.; Kim, H.; Yoshida, J.
    • Journal Title

      Angew. Chem. Int. Ed. 48

      Pages: 8063-8065

  • [Journal Article] Generations and Reactions of N-t-Bus-aziridinyllithiums Using Microreactors2009

    • Author(s)
      Nagaki, A.; Takizawa, E.; Yoshida, J.
    • Journal Title

      Chem. Lett. 38

      Pages: 1060-1061

  • [Journal Article] Allenylsilane Synthesis by Carbolithiation of Conjugated-enynes using Aryllithium in Microflow System.2009

    • Author(s)
      Tomida, Y.; Nagaki, A.; Yoshida, J.
    • Journal Title

      Org. Lett. 11

      Pages: 3614-1317

  • [Journal Article] Microflow System Controlled Anionic Polymerization of MMA2009

    • Author(s)
      Nagaki, A.; Tomida, Y.; Miyazaki. A.; Yoshida, J.
    • Journal Title

      Macromolecules 42

      Pages: 4384-4387

  • [Journal Article] Microflow Systems for Organic Synthesis: A New Synthetic Chemistry from Space Controlling Time.2009

    • Author(s)
      Yoshida, J.; Nagaki, A.
    • Journal Title

      Kagaku 64

      Pages: 22-26

  • [Journal Article] Synthesis of Unsymmetrically Substituted Biaryls via Sequential Lithiation of Dibromobiaryls Using Integrated Microflow Systems.2009

    • Author(s)
      Nagaki, A.; Takabayashi, N.; Tomida, Y.; Yoshida, J.
    • Journal Title

      Beilstein J. Org. Chem. 5,No16

  • [Journal Article] Generation and Reactions of a-Silyl Oxiranyllithium Using Microflow System.2009

    • Author(s)
      Nagaki, A.; Takizawa, E.; Yoshida, J.
    • Journal Title

      Chem. Lett. 38

      Pages: 486-487

  • [Journal Article] Oxiranyl Anion Methodology Using Microflow System2009

    • Author(s)
      Nagaki, A.; Takizawa. E.; Yoshida, J.
    • Journal Title

      J. Am. Chem. Soc. 131

      Pages: 1654-1655

  • [Journal Article] Aryllithium Compounds Bearing Alkoxycarbonyl Groups. Generation and Reactions Using a Microflow System.2008

    • Author(s)
      Nagaki, A.; Kim, H.; Yoshida, J.
    • Journal Title

      Angew. Chem. Int. Ed. 47

      Pages: 7833-7836

  • [Journal Article] Synthesis of Unsymmetrical Biaryls by Means of Mono-Selective Reaction of polyhaloarenes Using Integrated Microflow System2008

    • Author(s)
      Nagaki, A.; Takabayashi, N.; Tomida, Y.; Yoshida, J.
    • Journal Title

      Org. Lett. 18

      Pages: 3937-3940

  • [Journal Article] Microflow System Controlled Anionic Polymerization of Styrenes.2008

    • Author(s)
      Nagaki, A.; Tomida, Y.; Yoshida, J.
    • Journal Title

      Macromolecules 41

      Pages: 6322-6330

  • [Journal Article] Microflow System Controlled Carbocationic Polymerization of Vinyl Ethers2008

    • Author(s)
      Nagaki, A.; Iwasaki, T.; Kawamura, K.; Yamada, D.; Suga, S.; Ando, T.; Sawamoto, M.; Yoshida, J.
    • Journal Title

      Chem. Asian J. 3

      Pages: 1558-1567

  • [Journal Article] Flash Chemistry: Fast Chemical Synthesis Using Microreactors2008

    • Author(s)
      Yoshida, J.; Nagaki, A.; Yamada, T.
    • Journal Title

      Chem. Eur. J. 14

      Pages: 7450-7459

  • [Journal Article] Modern Strategies in Electroorganic Synthesis2008

    • Author(s)
      Yoshida, J.; Kataoka, K.; Horcajada, R.; Nagaki, A.
    • Journal Title

      Chem. Rev. 108

      Pages: 2265-2299

  • [Presentation] Unstable Aryllithiums Using Integrated Microflow Systems2010

    • Author(s)
      A. Nagaki, H Kim, Y. Tomida, N. Takabayashi, H. Usutani, J. Yoshida
    • Organizer
      The 11nd International Conference on Microreaction Technology, Kyoto Research Park
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      20100308-20100310
  • [Presentation] 有機合成反応へのマイクロリアクターの利用2009

    • Author(s)
      永木愛一郎、吉田潤一
    • Organizer
      INCHEM TOKYO 2009
    • Place of Presentation
      東京
    • Year and Date
      20091100
  • [Presentation] マイクロフローシステムを用いた不安定アリールリチウム種の発生・反応2009

    • Author(s)
      永木愛一郎、金ヒジン、高林尚史、富田裕、吉田潤一
    • Organizer
      第56回有機金属化学討論会
    • Place of Presentation
      京都
    • Year and Date
      20090900
  • [Presentation] アルキルメタクリルレート類のマイクロフロー精密アニオン重合反応2009

    • Author(s)
      永木愛一郎、宮崎豊生、富田裕、吉田潤一
    • Organizer
      第58回高分子討論会
    • Place of Presentation
      熊本
    • Year and Date
      20090900
  • [Presentation] マイクロフロー精密アニオン重合反応によるスチレン-アルキルメタクリルレート類のブロックポリマー合成2009

    • Author(s)
      永木愛一郎、宮崎豊生、吉田潤一
    • Organizer
      第58回高分子討論会
    • Place of Presentation
      熊本
    • Year and Date
      20090900
  • [Presentation] スチレン類のマイクロフロー精密アニオン重合反応による精密構造制御ポリマー合成2009

    • Author(s)
      永木愛一郎、富田裕、吉田潤一
    • Organizer
      第58回高分子討論会
    • Place of Presentation
      熊本
    • Year and Date
      20090900
  • [Presentation] Flash Chemistry: Fast Chemical Synthesis in Microflow Systems2009

    • Author(s)
      A. Nagaki, J. Yoshida
    • Organizer
      Proceedings of the Seventh International ASME Conference on Nanochannels, Microchannels and Minichannels (ICNMM2009) Pohang
    • Place of Presentation
      South Korea(invited)
    • Year and Date
      20090622-20090624
  • [Presentation] Generation and Reactions of ortho-Bromophenyllithium without Benzyne Formation Using Microflow System.2008

    • Author(s)
      A. Nagaki, Y. Usutani, H. Tomida, H Kim, N. Takabayashi, T. Nokami, H. Okamoto, J. Yoshida
    • Organizer
      The 10nd International Conference on Microreaction Technology
    • Place of Presentation
      New Orleans, US
    • Year and Date
      20080400
  • [Book] マイクロリアクターによる合成技術と工業生産(マイクロリアクターを用いたアニオン重合の制御)2009

    • Author(s)
      Nagaki, A.; Yoshida, J.
    • Total Pages
      147-159
    • Publisher
      サイエンス&テクノロジー
  • [Book] Polymerization: Cationic Living Polymeriation(Micro Process Engineering, Volume 2: Devices, Reactions and Applications., Chapter 14)2009

    • Author(s)
      Yoshida, J.; Nagaki, A.
    • Total Pages
      229-242
    • Publisher
      Wiley-VCH
  • [Book] Gas Phase and Gas/Liquid Phase Reactions: Substitution(Micro Process Engineering, Volume 2: Devices, Reactions and Applications., Chapter 8)2009

    • Author(s)
      Yoshida, J.; Nagaki, A.
    • Total Pages
      131-140
    • Publisher
      Wiley-VCH
  • [Book] Liquid Phase and Liquid/Liquid Phase Reactions: Oxidations and reductions(Micro Process Engineering, Volume 2: Devices, Reactions and Applications., Chapter 7)2009

    • Author(s)
      Yoshida, J.; Nagaki, A.
    • Total Pages
      109-125
    • Publisher
      Wiley-VCH
  • [Book] Liquid Phase and Liquid/Liquid Phase Reactions: Addition and elimination reactions(Micro Process Engineering, Volume 2: Devices, Reactions and Applications., Chapter 5.)2009

    • Author(s)
      Yoshida, J.; Nagaki, A.
    • Total Pages
      81-96
    • Publisher
      Wiley-VCH

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Published: 2011-06-18   Modified: 2016-04-21  

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