2009 Fiscal Year Final Research Report

Development of novel multi-drug time-lag sustained release sheet with targeting ability for high efficient cancer chemotherapy

Research Project

Project/Area Number	20790138
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Medical pharmacy
Research Institution	Kyushu University
Principal Investigator	OKUDA Tatsuya Kyushu University, 先導物質化学研究所, 助教 (50378791)
Project Period (FY)	2008 – 2009
Keywords	積層電界紡糸法 / ファイバーメッシュシート / 複数薬剤 / 時間差徐放 / DDS / 生分解性高分子
Research Abstract	In this study, we tried to establish the time-programmed multidrug sustained release system by using the multilayered electrospun fiber meshes. As the results, the time-programmed dual release system from single formulation was successfully established. The results obtained from this study are expected to be useful for not only the efficient implementation of combination therapy that generally performed in clinical chemotherapy but also improvement of patient's "quality of life". Furthermore, the results are also expected to contribute to improving the quality of medical.