2010 Fiscal Year Final Research Report
Analysis of the susceptibility gene for severe pneumonia with S.pneumoniae
Project/Area Number |
20790577
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Respiratory organ internal medicine
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Research Institution | Toho University |
Principal Investigator |
KIMURA Soichiro Toho University, 医学部, 助教 (60408870)
|
Project Period (FY) |
2008 – 2010
|
Keywords | 肺炎球菌 / Genotype / 肺炎 / マウス |
Research Abstract |
I explored the disease-susceptible genes associated with severe pneumonia with Streptococcus pneumoniae in mouse model. I identified candidate region within 10cM on chromosome 1 by using linkage analysis with CBA/J x C57B6/J F(2) intercross mouse. In this region, I confirmed possible disease-susceptibility-related genes such as immunoglobulin and apoptosis.
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Research Products
(1 results)