2009 Fiscal Year Final Research Report
Comparison of the nucleotide substitution rate of the hepatitis C virus in mothers and their infants
| Project/Area Number |
20790737
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Pediatrics
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| Research Institution | Nagoya City University |
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Principal Investigator |
ITO Koichi Nagoya City University, 大学院・医学研究科, 助教 (00444977)
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| Project Period (FY) |
2008 – 2009
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| Keywords | HCV遺伝子 / NS5B母子感染 |
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| Research Abstract |
The phylogenetic analysis of the NS5b region of the HCV genome was useful for proving mother-to-infant transmission of HCV. The evolution of NS5b did not increase in infants infected through mother-to-infant transmission in childhood. The lower immunological pressure generated by the infant host may affect viral evolution.
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[Presentation] Polymorphisms of the Factor VII Gene Associated with the Low Activities of Vitamin K-Dependent Coagulation Factors in One-Month-Old Infants.2008
Author(s)
Koichi Ito, Kenji Goto, Tokio Sugiura, Kanji Muramatsu, Toshihiro Ando, Hiroko Maniwa, Takao Yokoyama, Kohachiro Sugiyama, Hajime Togari
Organizer
World Congress of Pediatric Gastroenterology, Hepatology and Nutrition.
Place of Presentation
Iguassu, Brazil
Year and Date
20080816-20080820
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