2009 Fiscal Year Final Research Report
Neuroimaging study about the cognitive impairment of vascular depression
| Project/Area Number |
20790841
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Psychiatric science
|
|---|
| Research Institution | Hiroshima University |
|---|
Principal Investigator |
OKADA Go Hiroshima University, 大学院・医歯薬学総合研究科, 特任助教 (10457286)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Keywords | 血管性うつ病 / 認知機能 / 機能的MRI / 言語流暢性課題 |
|---|
| Research Abstract |
To characterize the functional neuroanatomy of vascular depression, recovered patients with late-onset major depressive disorder were classified as SCI-positive and SCI-negative. Both groups completed verbal fluency task during functional MRI assessment. The verbal fluency performance was significantly lower in the SCI-positive group than in the SCI-negative group. In functional connectivity analysis, SCI-positive group had a significantly reduced functional connectivity between the anterior cingulate cortex and left frontal cortex during a verbal fluency task.
|
