2009 Fiscal Year Final Research Report
Study for utility of normal pressure hypoxic training before extensive pulmonary resection.
| Project/Area Number |
20790984
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Thoracic surgery
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| Research Institution | Gifu University |
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Principal Investigator |
MATSUMOTO Shinsuke Gifu University, 大学院・医学系研究科, 非常勤講師 (40397352)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 外科 / 肺切除術 / トレーニング |
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| Research Abstract |
We evaluated the influence of respiration/circulation following extensive pulmonary resection in rats. We started manufacture of normal pressure hypoxic training model, however, it is not completed. On the other hand, we evaluated the influence of respiration/circulation after pulmonary resection by granulocyte colony-stimulating factor (G-CSF). G-CSF administration suppressed pulmonary hypertension/right ventricular hypertrophy, thus preventing right heart failure after resection. We will train rats before pulmonary resection, and evaluate a further effect.
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[Journal Article] Suppression of right ventricular hypertrophy after extensive pulmonary resection in rats by granulocyte colony-stimulating factor
Author(s)
Shinsuke Matsumoto, Hisashi Iwata, Koyo Shirahashi, Masanao Saio, Yukio Umeda, Tsutomu Marui, Narihiro Ishida, Masaki Kimura, Takuya Sugimoto, Hideaki Manabe, Hirofumi Takemura
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Journal Title
Journal of Sugical Research (in press)
Peer Reviewed
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