2009 Fiscal Year Final Research Report
Analysis for control systems of heme oxygenase-1 in human villus cells and development for immunohistochemical staining of heme oxygenase-1 in human placenta
| Project/Area Number |
20791160
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Jichi Medical University |
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Principal Investigator |
SUZUKI Hirotada Jichi Medical University, 医学部, 助教 (90406116)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 産科学 |
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| Research Abstract |
We cultured primary human trophoblast or BeWo cell with ZuPP (heme oxygenase-1 inhibitor) and analized the mRNA levels of soluble fms-like tyrosine kinase-1 (sFlt-1) and soluble endoglin (sEng) by RT-RCR. These mRNA levels did not change.
We are now collecting human placenta tissues. In future, we will try immunohistochemical staining of heme oxygenase-1 in these placenta tissues.
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