2009 Fiscal Year Final Research Report
Analysis of the mechanisms between preterm birth and periodontal diseases.
| Project/Area Number |
20791354
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Functional basic dentistry
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| Research Institution | Yamaguchi University |
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Principal Investigator |
TAKII Ryousuke Yamaguchi University, 大学院・医学系研究科, 助教 (00419558)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 歯科薬理学 |
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| Research Abstract |
Recent etpidemiological study showed that periodontal disease is a risk factor of preterm birth and low birth weight. Periodontal disease is a chronic inflammatory process and it is thought that the origin is infection by oral bacteria. These results indicate that gingipains inhibitors may be not the medication for periodontal disease, but also the preventive medicine for preterm birth and low birth weight by periodontal disease.
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[Journal Article] Heat Shock Transcription Factor 1 Inhibits Expression of IL-6 through Activating Transcription Factor 32010
Author(s)
Ryosuke Takii, Sachiye Inouye, Mitsuaki Fujimoto, Tamami Nakamura, Toyohide Shinkawa, Ramachandran Prakasam, Ke Tan, Naoki Hayashida, Hitoshi Ichikawa, Tsonwin Hai, Akira Nakai
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Journal Title
J. Immunol 184
Pages: 1041-1048
Peer Reviewed
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