2010 Fiscal Year Final Research Report
Investigation of the mechanism of osteocalcin expression and VEGF induction in human dental pulp cells.
| Project/Area Number |
20791504
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Gifu University |
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Principal Investigator |
HATAKEYAMA Daijiro Gifu University, 医学系研究科, 助教 (60377653)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 歯髄組織幹細胞 / オステオカルシン / 血管内皮増殖因子 / 誘導機構の解析 |
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| Research Abstract |
Bone morphogenetic protein -2, -4 induces osteocalcin expression and vascular endothelial growth factor accumulation via p38 and p44/p42 mitogen activated protein kinases in human osteoblastic cells induced by human dental pulp stem cells. Moreover, it is suggested that the expression levels of vascular endothelial growth factor are very high in oliginal human dental pulp stem cells.
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