2009 Fiscal Year Final Research Report
Clarification of pain mechanism and pain control during orthodontic treatment
| Project/Area Number |
20791574
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
YABUUCHI Toshinori Okayama University, 岡山大学病院, 医員 (00452582)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 神経ペプチド / 痛み / 共焦点顕微鏡 / 組織学的形態計測 |
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| Research Abstract |
We found that the distribution of various markers in central have been changed over time during tooth movement. In trigeminal ganglion, we found that microglia and astrocytes were activated during tooth movement. In addition, activated glial cells were localized around the Fos-positive neurons. The results of studies were suggested glial cells may have been deeply involved in noxious stimulation during tooth movement.
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