2009 Fiscal Year Final Research Report
Molecular mechanism of phosphatidylserine exposure in apoptotic cells
| Project/Area Number |
20890109
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
General physiology
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| Research Institution | Kyoto University |
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Principal Investigator |
SUZUKI Jun Kyoto University, 医学研究科, 特定研究員(科学研究) (30511894)
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| Project Period (FY) |
2008 – 2009
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| Keywords | アポトーシス / ホスファチジルセリン / カルシウム |
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| Research Abstract |
I investigated the mechanisms of phosphatidylserine (PS) exposure in apoptotic cells. Ca^<2+> was found to be the effecter for PS exposure. Using Ca2+ ionophore A23187, I designed the experimental system in which cells externalize PS without dying.
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