2009 Fiscal Year Final Research Report

Construction of diagnostic probability system indicate cervical lymph node metastasis using MRI

Research Project

Project/Area Number	20890275
Research Category	Grant-in-Aid for Young Scientists (Start-up)
Allocation Type	Single-year Grants
Research Field	Pathobiological dentistry/Dental radiology
Research Institution	Fukuoka Dental College
Principal Investigator	FUKUNARI Fumiko Fukuoka Dental College, 歯学部, 医員 (30510234)
Project Period (FY)	2008 – 2009
Keywords	頸部リンパ節 / 口腔癌 / リンパ節転移 / MRI
Research Abstract	1. MR images obtained before surgery were correlated with the histopathological architecture of the cervical lymph nodes from oral squamous cell carcinoma obtained by neck dissection. On T2-weighted images, Very hyperintese and isointense areas were specific findings for lymph nodes containing metastases. On diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) images, it was difficult to differentiate metastatic from benign lymph nodes. 2. The positive predictive value (PPV) of each MRI findings, such as the signal intensity of the lymph node parenchyma on T2-weighted images, the pattern of signal intensity curve in dynamic MRI, were calculated. Using the PPV defined as diagnostic probability, the diagnostic results of cervical lymph node metastasis from oral squamous cell carcinoma using MRI may be quantitated.