粘弾性マイクロジェットの能動制御と次世代製造プロセスへの展開

2023 Fiscal Year Annual Research Report

• Project/Area Number: 20H00223
• Research Institution: Tokyo University of Agriculture and Technology
• Principal Investigator: 田川 義之 東京農工大学, 工学(系)研究科(研究院), 教授 (70700011)
• Co-Investigator(Kenkyū-buntansha): 安藤 景太 慶應義塾大学, 理工学部(矢上), 准教授 (30639018) ; 山中 晃徳 東京農工大学, 工学(系)研究科(研究院), 教授 (50542198) ; 長津 雄一郎 東京農工大学, 工学(系)研究科(研究院), 教授 (60372538) ; 田中 あかね 東京農工大学, (連合)農学研究科(研究院), 教授 (80418673)
• Project Period (FY): 2020-04-01 – 2024-03-31
• Keywords: マイクロジェット / 粘弾性流体 / レオロジー計測 / 無針注射 / 高粘度ジェット / 液滴塗布

Outline of Annual Research Achievements

本研究では衝撃力を利用した超音速・高粘度マイクロ液体ジェット生成法(代表者の開発技術)に基づき、ジェットの伸長・分裂・衝突という医学・工学応 用に不可欠な各要素の物理機構解明・能動制御を達成するため、次世代製造プロセスにとって需要の高い粘弾性液体ジェットに焦点を絞り、学術的に未解明な特徴的挙動を解明に取り組み続けている。
2023年度は主に次世代製造プロセスの実現に向けた学術課題に取り組んだ。
まず、無針注射器による生体組織への貫入については、皮膚からジェット射出口までの距離の影響を系統的に調査した。これまで、代表者は分担者と協力し、高速ジェットをラット皮膚へ衝突させる実験を行っており、その結果と比較し、貫入深さと距離の関係および貫入深さの決定メカニズムについて調査した。新たに数値計算を援用し、運動量流束密度によって説明できることを明らかにした（Igarashi, Tagawa et al., Phys. Fluids 2024）。
次に、軟質材料印刷における液滴と着弾壁面組織との相互作用について研究を進めた。ウェアラブル(バイオ)印刷に向けて、液滴着弾時の軟質材料と液滴の相互作用を解明するために、生体模擬組織であるゼラチンに液滴を衝突させ、その非定常応力分布を計測した。これまで固体板への衝突現象との差異が報告されていたが、その原因である軟質材料の影響、特に軟質材料の変形と材料内応力場についての知見が得られていなかった。そこで、高速度偏光カメラを用いた光弾性法により応力分布を計測し、粘弾性を考慮した数値計算を通じて、生体材料内の応力分布を解析した。この成果に基づいて、液滴の射出条件（液滴径，衝突速度）に応じた応力負荷をモデル化し(Yokoyama, Tagawa et al., Optics and Lasers in Eng. 2024)、生体負荷（痛み）の定量化を目指した。

Research Progress Status

令和5年度が最終年度であるため、記入しない。

Strategy for Future Research Activity

令和5年度が最終年度であるため、記入しない。

Research Products

• [Int'l Joint Research] 清華大学(中国)
  • Country Name: CHINA
  • Counterpart Institution: 清華大学
• [Journal Article] The effects of secondary cavitation position on the velocity of a laser-induced microjet extracted using explainable artificial intelligence (2024)
  • Author(s): Igarashi Daichi、Yee Jingzu、Yokoyama Yuto、Kusuno Hiroaki、Tagawa Yoshiyuki
  • Journal Title: Physics of Fluids Volume: 36 Pages: 013317
  • DOI: 10.1063/5.0183462
  • Peer Reviewed / Open Access
• [Journal Article] Optimal standoff distance for a highly focused microjet penetrating a soft material (2024)
  • Author(s): Igarashi Daichi、Kimura Kento、Endo Nanami、Yokoyama Yuto、Kusuno Hiroaki、Tagawa Yoshiyuki
  • Journal Title: Physics of Fluids Volume: 36 Pages: 042005
  • DOI: 10.1063/5.0202757
  • Peer Reviewed / Open Access
• [Journal Article] High-speed photoelastic tomography for axisymmetric stress fields in a soft material: Temporal evolution of all stress components (2024)
  • Author(s): Yokoyama Yuto、Ichihara Sayaka、Tagawa Yoshiyuki
  • Journal Title: Optics and Lasers in Engineering Volume: 178 Pages: 108224～108224
  • DOI: 10.1016/j.optlaseng.2024.108224
  • Peer Reviewed / Open Access
• [Journal Article] Interactions of a collapsing laser-induced cavitation bubble with a hemispherical droplet attached to a rigid boundary (2023)
  • Author(s): Ren Z., Han, H., Zeng, H., Sun, C., Tagawa, Y., Zuo, Z. and Liu, S.
  • Journal Title: Journal of Fluid Mechanics Volume: 976 Pages: A11
  • DOI: 10.1017/jfm.2023.895
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Double-pass imaging background-oriented Schlieren technique for focusing on measurement target (2023)
  • Author(s): Hirose, Y., Yamagishi, M., Udagawa, S., Inage, T., Tagawa, Y. and Ota, M.
  • Journal Title: Experiments in Fluids Volume: 64 Pages: 151
  • DOI: 10.1007/s00348-023-03694-9
  • Peer Reviewed / Open Access
• [Presentation] Polarization measurement of flow structure around a moving bubble/solid in a quiescent liquid (2023)
  • Author(s): Kusuno H., Tagawa Y.
  • Organizer: 11th International Conference on Multiphase Flow
  • Int'l Joint Research
• [Presentation] Photoelastic measurement and numerical investigation on viscous fingering (2023)
  • Author(s): Kawaguchi M., Yagi H., Suzuki X R., Muto M., Nagatsu Y., Tagawa Y.
  • Organizer: 11th International Conference on Multiphase Flow
  • Int'l Joint Research
• [Presentation] Prediction of Deformation of a Drop during an Impact on a Solid Surface using an Encoder-Decoder (2023)
  • Author(s): Yee J., Igarashi D., Miyatake S., Tagawa Y.
  • Organizer: 11th International Conference on Multiphase Flow
  • Int'l Joint Research
• [Presentation] Non-Contact Measurement of Ultrasound Pressure Field using Background-Oriented Schlieren Technique (2023)
  • Author(s): Ichihara S., Kurashina Y., Tagawa Y.
  • Organizer: 11th International Conference on Multiphase Flow
  • Int'l Joint Research
• [Presentation] On viscoelastic bungee jet induced by impact (2023)
  • Author(s): Kamamoto K., Watanabe H., Hosokawa A., Tagawa Y.
  • Organizer: 11th International Conference on Multiphase Flow
  • Int'l Joint Research
• [Presentation] Development of a stress field visualization method for dynamic fluids on channel walls (2023)
  • Author(s): Sekiguchi S., Kobayashi U. K., Kurashina Y., Morikawa K., Tagawa Y.
  • Organizer: 11th International Conference on Multiphase Flow
  • Int'l Joint Research
• [Presentation] Phase diagram of bungee-type behavior of impulsively-induced viscoelastic liquid jets (2023)
  • Author(s): Hosokawa A., Watanabe H., Kamamoto K., Kusuno H., Kobayashi U. K., Tagawa Y.
  • Organizer: 11th International Conference on Multiphase Flow
  • Int'l Joint Research
• [Presentation] Non-contact measurement of ultrasonic acoustic field in water with cavitation bubble using background-oriented schlieren technique (2023)
  • Author(s): Ichihara S., Tagawa Y.
  • Organizer: 7th Cavitation and Multiphase flows Workshop
  • Int'l Joint Research
• [Presentation] Automation of drop impact experiment (2023)
  • Author(s): Miyatake S., Yee J., Tagawa Y.
  • Organizer: ASME-JSME-KSME Fluids Engineering Division 2023
  • Int'l Joint Research
• [Presentation] High-speed focused jet for the development of impact-induced needle-free injector (2023)
  • Author(s): Yamagata K., Sekiguchi S., Watanabe H., Yokoyama Y., Tagawa Y.
  • Organizer: ASME-JSME-KSME Fluids Engineering Division 2023
  • Int'l Joint Research
• [Presentation] Effects of vessel geometry on the behavior of impact-induced focused liquid jets (2023)
  • Author(s): Watanabe H., Kusuno H., Yamagata K., Yokoyama Y., Tagawa Y.
  • Organizer: ASME-JSME-KSME Fluids Engineering Division 2023
  • Int'l Joint Research
• [Presentation] Three-dimensional reconstruction of fluid stress field from flow birefringence using 3D physics informed convolutional encoderdecoder (3D-PICED) (2023)
  • Author(s): Igarashi D., Yee J., Tagawa Y.
  • Organizer: ASME-JSME-KSME Fluids Engineering Division 2023
  • Int'l Joint Research
• [Presentation] Measurement of stress-optic coefficients of birefringent fluids for measuring a three-dimensional stress field (2023)
  • Author(s): Worby W. K., Nakamine K., Yokoyama Y., Muto M., Tagawa Y.
  • Organizer: ASME-JSME-KSME Fluids Engineering Division 2023
  • Int'l Joint Research
• [Presentation] Critical morphological features of a splashing drop extracted through video classification using an explainable feedforward neural network (FNN) (2023)
  • Author(s): Yee J., Igarashi D., Miyatake S., Yamanaka A., Tagawa Y.
  • Organizer: ASME-JSME-KSME Fluids Engineering Division 2023
  • Int'l Joint Research
• [Presentation] On-demand Painting of Highly-viscous Liquids (2023)
  • Author(s): Tagawa Y.
  • Organizer: 11th International Conference on Materials for Advanced Technologies
  • Int'l Joint Research / Invited
• [Presentation] Integrated photoelasticity in gels for 3D stress field measurements (2023)
  • Author(s): Tagawa Y., Ichihara S., Yokoyama Y.
  • Organizer: 9IDMRCS
  • Int'l Joint Research
• [Presentation] The generation and dynamics of a granular jet induced by a sudden acceleration (2023)
  • Author(s): Kobayashi K.
  • Organizer: 9IDMRCS
  • Int'l Joint Research
• [Presentation] Construction of an automated drop impact system for AI-based drop impact study (2023)
  • Author(s): Miyatake S., Kumagai S., Yee J., Tagawa Y.
  • Organizer: Droplets 2023
  • Int'l Joint Research
• [Presentation] Interpolated Prediction of the Morphology of a Splashing Drop from Physical Parameters using an Image-Based Explainable Artificial Intelligence (2023)
  • Author(s): Yee J., Igarashi D., Miyatake S., Yamanaka A., Tagawa Y.
  • Organizer: Droplets 2023
  • Int'l Joint Research
• [Presentation] Splashing of impacting micron-sized droplets (2023)
  • Author(s): Tagawa Y.
  • Organizer: Droplets 2023
  • Int'l Joint Research / Invited
• [Presentation] Photoelastic Measurement of Finger Growth in Saffman-Taylor Instability (2023)
  • Author(s): Kawaguchi M., Suzuki R. X., Nagatsu Y., Tagawa Y.
  • Organizer: 20th International Symposium on Flow Visualization
  • Int'l Joint Research
• [Presentation] 3D stress-field measurement in multiphase flows (2023)
  • Author(s): Tagawa Y.
  • Organizer: PoF25
  • Int'l Joint Research
• [Presentation] Effect of convergent-shaped vessel on the velocity of impact-induced focused liquid jets (2023)
  • Author(s): Watanabe H., Yamagata K., Yokoyama Y., Kusuno H., Tagawa Y.
  • Organizer: APS DFD 2023
  • Int'l Joint Research
• [Presentation] How does the flow structure of a gradually contaminating bubble evolve (2023)
  • Author(s): Kusuno H., Tagawa Y.
  • Organizer: APS DFD 2023
  • Int'l Joint Research
• [Presentation] Role of friction in granular Plateau-Rayleigh instability (2023)
  • Author(s): Pradipt P., Tagawa Y.
  • Organizer: APS DFD 2023
  • Int'l Joint Research
• [Presentation] Spatio-temporal measurement of underwater ultrasound field using non-contact technique (2023)
  • Author(s): Ichihara S., Kurashina Y., Tagawa Y.
  • Organizer: APS DFD 2023
  • Int'l Joint Research
• [Presentation] Viscoelastic bungee jetting induced by an impulsive force (2023)
  • Author(s): Kamamoto K., Hosokawa A., Tagawa Y.
  • Organizer: APS DFD 2023
  • Int'l Joint Research
• [Presentation] Making Beaker Jump By Vapor Bubble Actuation (2023)
  • Author(s): Hosokawa A., Kobayashi K., Tagawa Y.
  • Organizer: APS DFD 2023
  • Int'l Joint Research
• [Presentation] Stress Field Mesurement in Jeffery-Hammel Flow (2023)
  • Author(s): Kobayashi M., Worby W. K., Kawaguchi M., Tagawa Y.
  • Organizer: APS DFD 2023
  • Int'l Joint Research
• [Presentation] Unsteady stress field measurement during droplet impact on soft materials using photoelastic tomography (2023)
  • Author(s): Yokoyama Y., Ichihara S., Tagawa Y.
  • Organizer: APS DFD 2023
  • Int'l Joint Research
• [Presentation] Stress field visualization of Saffman-Taylor instability in Hele-Shaw cell (2023)
  • Author(s): Kawaguchi M., Worby W. K., Suzuki R., Nagatsu Y., Tagawa Y.
  • Organizer: APS DFD 2023
  • Int'l Joint Research
• [Presentation] Three-dimensional stress measurement of a laminar flow in a rectangular channel using integrated photoelasticity (2023)
  • Author(s): Tagawa Y., Kento N., Worby W. K., Yokoyama Y.
  • Organizer: APS DFD 2023
  • Int'l Joint Research
• [Presentation] Calibration of stress-optic coefficients for visualizations of fluid stress fields (2023)
  • Author(s): Worby W. K., Nakamine K., Yokoyama Y., Bando Y., Kawaguchi M., Kusuno H., Tagawa Y.
  • Organizer: APS DFD 2023
  • Int'l Joint Research
• [Remarks] 研究紹介サイト
  • URL: http://web.tuat.ac.jp/~tagawayo/