2023 Fiscal Year Final Research Report
Unseen deep biosphere: organic molecules in anoxic primitive prokaryotic cell.
Project/Area Number |
20H02019
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Review Section |
Basic Section 17050:Biogeosciences-related
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Research Institution | Japan Agency for Marine-Earth Science and Technology |
Principal Investigator |
TAKANO Yoshinori 国立研究開発法人海洋研究開発機構, 海洋機能利用部門(生物地球化学センター), センター長代理 (80399815)
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Project Period (FY) |
2020-04-01 – 2024-03-31
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Keywords | アーキア(古細菌) / 共通祖先 / 有機分子レベル分析技術 / 生命の系統樹 / ロキアーキオータ(Lokiarchaeaota) |
Outline of Final Research Achievements |
Archaea, called Lokiarchaeota, is a major focus of attention as the most promising candidate for the origin of eukaryotes. The reason is that it is considered to be the common ancestor of Archaea and Eukarya. However, their essential nature from a scientific point of view has remained a great mystery. Then, we have successfully isolated and cultured its common ancestor (Imachi et al., Nature, 2020). The purpose of this study was to clarify the cellular style of the common ancestor of the two major life forms from the oldest extant primitive depictions of life on the Earth (i.e., isolates), and to reveal the actual image of their primordial metabolic mechanisms.
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Free Research Field |
地球惑星科学・地球生命科学
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Academic Significance and Societal Importance of the Research Achievements |
世界中の研究者らが、熱望している「アーキア(古細菌)とユーカリア(真核生物)の共通祖先」の単離株を初めて捕獲した。我々は、有機分子レベル分析技術を用いて、地球最古の「共通祖先」の細胞様式と始原的な代謝機構の実像を解明し、原核から真核へ生命の系統樹の進化を明らかにした(Imachi et al.,Nature, 2020)。高精度な分析技術と先進的な物質科学の相乗効果である。このような技術基盤は、領域を超えた学術界への波及に限らず、革新的な研究開発を生み出す新知識の社会還元に貢献する。一連の実績評価を受け、米国科学協会(AAAS)Science誌 のブレイクスルーオブザイヤーに選出された。
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