2022 Fiscal Year Final Research Report
Antioxidative activity of plant secondary metabolites and oxidation of biological components
| Project/Area Number |
20K05854
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Review Section |
Basic Section 38040:Bioorganic chemistry-related
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| Research Institution | Toyo University |
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Principal Investigator |
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| Project Period (FY) |
2020-04-01 – 2023-03-31
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| Keywords | 酸化ストレス / シロイヌナズナ / 抗酸化物質 / 脂質酸化物 / 核酸酸化物 |
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| Outline of Final Research Achievements |
Plants are subjected to various stresses from their growing environment. Plants are thought to have various stress tolerance mechanisms to protect themselves from these stresses. One of them is the antioxidant activity of antioxidants. In this study, we used scopoletin biosynthesis-deficient mutant and wild-type Arabidopsis to clarify which biocomponents is involved in protecting function by antioxidative activity of scopoletin. We focuced on oxides of nucleic acids, fatty acids, and proteins generated in stressed plants. As a result, the plants that cannot accumulate scopoletin accumulated more of these components than the wild-type plants.
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| Free Research Field |
植物生化学
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| Academic Significance and Societal Importance of the Research Achievements |
これまで植物の蓄積する抗酸化物質はその抗酸化活性から推測して、酸化ストレスに対する耐性に関わっていると考えられてきた。本研究はシロイヌナズナが蓄積するスコポレチンもしくはその関連物質が、酸化ストレス受容時に実際に核酸や脂肪酸、タンパク質の酸化を抑制していることを示した。本研究で得られた知見は、農作物や自然環境に自生する植物の定量的ストレスモニタリングのための基礎的知見となる。
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