Plant immunity regulation via ubiquitin signals on membrane trafficking

2023 Fiscal Year Final Research Report

• Project/Area Number: 20K05949
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 38060:Applied molecular and cellular biology-related
• Research Institution: Hokkaido University
• Principal Investigator: Sato Takeo 北海道大学, 理学研究院, 准教授 (50609724)
• Project Period (FY): 2020-04-01 – 2024-03-31
• Keywords: 環境応答 / ユビキチンリガーゼ

Outline of Final Research Achievements

In this study, we investigated the molecular mechanism regulating plant resistance to pathogen attack via the ubiquitin signals on membrane trafficking. We focused on the biochemical and physiological functions of membrane localized ubiquitin ligase ATL31. As results, we found ATL31 physically interacts with a TGN/EE-SNARE protein. This interaction is required for the proper subcellular localization and physiological function of ATL31. In addition, we found the TGN/EE-SNARE protein was decorated by K63-type ubiquitin chain in plants.

Free Research Field

植物科学

Academic Significance and Societal Importance of the Research Achievements

植物免疫機構の理解は，農作物の収量向上を実現する上で重要な課題である。本研究から，これまであまり知られていなかった膜交通系の機能制御機構やユビキチンシグナルの機能性が見出された。本研究成果は，植物免疫を制御する分子基盤の理解に貢献するものである。