Study on high safety human interface based on measurement of brain function during transient cerebral hypoperfusion

2023 Fiscal Year Final Research Report

• Project/Area Number: 20K11902
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Review Section: Basic Section 61020:Human interface and interaction-related
• Research Institution: Chiba University
• Principal Investigator: ISHIBASHI Keita 千葉大学, デザイン・リサーチ・インスティテュート, 准教授 (40325569)
• Co-Investigator(Kenkyū-buntansha): 赤間 章英 前橋工科大学, 工学部, 助教 (00847733)
• Project Period (FY): 2020-04-01 – 2024-03-31
• Keywords: 脳血流調節 / 脳機能 / ヒューマンインタフェース / 事象関連電位 / 聴性脳幹反応

Outline of Final Research Achievements

The present study focused on changes in human brain function during a transient decrease in cerebral blood flow caused by sinusoidal lower-body negative pressure to investigate evaluation methods for human interfaces that can be used in severe conditions where brain function is not fully preserved. The experimental results showed that fluctuations in cerebral blood flow affected responses in the brainstem, which is the entry point for information, but not event-related potentials, which reflect higher cognitive function. This result suggests the robustness of higher brain functions to fluctuations in cerebral blood flow. In contrast, the existence of compensatory effects on other brain functions is an issue for further investigation.

Free Research Field

人間工学

Academic Significance and Societal Importance of the Research Achievements

脳血流と脳機能の関係についてこれまで多くの検討がなされてきたが，立ちくらみ様の一過性の脳血流低下時における脳機能の変化は，脳血流を高い再現性で変動させる手法が普及していないこともあり研究例も限られていた。今回の研究では，正弦波下半身陰圧負荷が高い再現性で脳血流を変動させる手法であることが明らかとなった，また，脳血流変動時の脳機能の変化を脳幹部の反応と高次の処理を反映する事象関連電位の両方で確かめることができた。これら点で学術的な意義があったものと考える。