2022 Fiscal Year Final Research Report
Development of Ln-polyoxometalate complex for imaging probe
| Project/Area Number |
20K15308
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 34020:Analytical chemistry-related
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2020-04-01 – 2023-03-31
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| Keywords | ポリオキソメタレート / ランタニド / エネルギー移動発光 / 速度論的安定性 |
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| Outline of Final Research Achievements |
The objective of this research is development of Ln-POM complex for imaging probe. Using SiW10O36 (SiW) as a POM ligand, Eu-SiW complex was successfully synthesized. The Eu-SiW complex showed energy-transfer luminescence from SiW ligand to Eu center, In addition, has high kinetic stability.
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| Free Research Field |
分析化学
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| Academic Significance and Societal Importance of the Research Achievements |
イメージングプローブの開発において，プローブの機能向上は病気の早期発見やプローブ使用量低減といった社会的意義がある．ランタニド錯体を用いたプローブの中でもポリオキソメタレートを無機配位子としたプローブは従来のプローブ設計とは一線を画すものであり，分析化学分野での学術的意義は大きい．
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