Establishment of a Novel Objective Evaluation and Differentiation Method for Daytime Sleepiness - Application of Auditory Information Processing Response of EEG

2023 Fiscal Year Final Research Report

• Project/Area Number: 20K16643
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 52030:Psychiatry-related
• Research Institution: Tokyo Medical and Dental University
• Principal Investigator: Takagi Shunsuke 東京医科歯科大学, 大学院医歯学総合研究科, 講師 (80806381)
• Project Period (FY): 2020-04-01 – 2024-03-31
• Keywords: 睡眠 / 眠気 / 聴覚刺激 / 脳波

Outline of Final Research Achievements

A system was established in which the auditory steady-state response (ASSR) sound stimulus itself was output from a speaker and input as an analog signal through a microphone to a Philips polysomnography device. Cases were accumulated and analyzed at Koishikawa Tokyo Hospital and Tokyo Medical and Dental University Hospital as a form of collaborative research. The analysis method was a Python-based module called MNE. The analysis suggested the possibility that the response of the ASSR may differ in a sleepy state, but the number of cases was small and did not lead to clear results.

Free Research Field

睡眠　てんかん

Academic Significance and Societal Importance of the Research Achievements

眠気は本人の不快感や社会的評価の低下につながるのみでなく、事故やエラーにつながって社会的な損失に至ることもあるため正確な評価が望まれている。現在は眠気の検査は反復睡眠潜時検査という実際に対象者に寝てもらう検査が使用されているが、これには非常に時間がかかるとともに、不正確であることが知られている。そのため今回の研究では聴覚刺激を用いた脳波反応で眠気を客観的・他覚的に評価する手法の探索を行なった。