Understanding the changes and current status of HIV treatment in Japan using open data

2023 Fiscal Year Final Research Report

• Project/Area Number: 20K18892
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 58010:Medical management and medical sociology-related
• Research Institution: Toho University
• Principal Investigator: Tanaka Hiroyuki 東邦大学, 薬学部, 准教授 (30747770)
• Project Period (FY): 2020-04-01 – 2024-03-31
• Keywords: HIV感染症 / 抗HIV薬 / NDBオープンデータ / 処方実態 / JADER / 副作用

Outline of Final Research Achievements

Our survey and analysis using NDB Open Data revealed the actual use of anti-HIV drugs over a 5-year period from FY2015 to FY2019. Additionally, through a survey and analysis using JADER, we uncovered changes over time in adverse drug event reports among PLWH due to the development of new anti-HIV drugs and changes in cART recommended in treatment guidelines. This study demonstrates that the use of NDB Open Data and JADER enables a relatively easy understanding of the actual status of anti-HIV drug prescriptions and adverse event reporting throughout Japan, highlighting the usefulness of utilizing open data in this field.

Free Research Field

HIV感染症

Academic Significance and Societal Importance of the Research Achievements

抗HIV薬の使用状況と副作用報告の実態を明らかにすることは、HIV診療に発展をもたらしうる新たな基礎資料となるため、学術的、社会的の両面において意義がある。また、この分野におけるNDBオープンデータやJADERの利用の有用性を示すことは、オープンデータのさらなる可能性を見出す点においても学術的な意義をもたらすものである。